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Article

Clinical significance of mutations in dihydropteroate synthase in Pneumocystis jirovecii pneumonia among non-HIV-infected patients.

International journal of antimicrobial agents - 1 Jan 2024

Liao Ting-Yu, Huang Yu-Tsung, Lee Tai-Fen, Hsueh Po-Ren, Yu Chong-Jen, Chien Jung-Yien

Abstract excerpt

BACKGROUND: Dihydropteroate synthase (DHPS) mutations may be associated with trimethoprim-sulfamethoxazole resistance in Pneumocystis jirovecii pneumonia (PCP) and worse clinical outcomes. However, the clinical significance of DHPS mutations in PCP among non-human immunodeficiency virus (HIV)-infected patients remains unclear. METHODS: Patients with PCP in three tertiary referral hospitals in Taiwan between 2016...

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Identifiers

PMID: 37925109
DOI: 10.1016/j.ijantimicag.2023.107019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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