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Article

Absence of dihydropteroate synthase mutations in Pneumocystis jirovecii from Brazilian AIDS patients.

The Journal of eukaryotic microbiology - 1 Jan 2000

Wissmann Gustavo, Alvarez-Martinez Míriam J, Meshnick Steven R, Dihel Ada R S, Prolla João C

Abstract excerpt

Several studies from developed countries have documented the association between trimethoprim-sulfamethoxazole prophylaxis failure and mutations in the Pneumocystis jirovecii gene coding for dihydropteroate synthase (DHPS). DNA was extracted from Giemsa-stained smears of 70 patients with P. jirovecii pneumonia seen in Porto Alegre, Brazil, from 1997 to 2004. Successful PCR amplification of the DHPS locus was...

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Share to Acquired Immunodeficiency Syndrome
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bronchoalveolar Lavage Fluid

Share to Dihydropteroate Synthase

Share to Drug Resistance, Fungal

Share to Pneumocystis carinii

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Source

Identifiers

PMID: 16872298
DOI: 10.1111/j.1550-7408.2006.00104.x

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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