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Article

Absence of dihydropteroate synthase mutations in Pneumocystis jirovecii from Brazilian AIDS patients.

The Journal of eukaryotic microbiology - 1 Jan 2000

Wissmann Gustavo, Alvarez-Martinez Míriam J, Meshnick Steven R, Dihel Ada R S, Prolla João C

Abstract excerpt

Several studies from developed countries have documented the association between trimethoprim-sulfamethoxazole prophylaxis failure and mutations in the Pneumocystis jirovecii gene coding for dihydropteroate synthase (DHPS). DNA was extracted from Giemsa-stained smears of 70 patients with P. jirov...

Read the complete abstract on PubMed

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Share to Acquired Immunodeficiency Syndrome
Share to AIDS-Related Opportunistic Infections
Share to Bronchoalveolar Lavage Fluid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dihydropteroate Synthase

Share to Drug Resistance, Fungal

Share to Pneumocystis carinii

Share to Pneumonia, Pneumocystis

Share to Trimethoprim

Source

Identifiers

PMID: 16872298
DOI: 10.1111/j.1550-7408.2006.00104.x

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16872298-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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