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Article

Mutational analysis of transmembrane regions 3 and 4 of SecY, a central component of protein translocase.

Journal of bacteriology - 1 Jun 2004

Mori Hiroyuki, Shimokawa Naomi, Satoh Yasunari, Ito Koreaki

Abstract excerpt

The SecYEG heterotrimeric membrane protein complex functions as a channel for protein translocation across the Escherichia coli cytoplasmic membrane. SecY is the central subunit of the SecYEG complex and contains 10 transmembrane segments (TM1 to TM10). Previous mutation studies suggested that TM3 and TM4 are particularly important for SecY function. To further characterize TM3 and TM4, we introduced a series of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15175310
DOI: 10.1128/JB.186.12.3960-3969.2004
PMCID: PMC419966

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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