Genetic analysis of SecY: additional export-defective mutations and factors affecting their phenotypes.

doi:10.1007/BF00301061

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Article

Genetic analysis of SecY: additional export-defective mutations and factors affecting their phenotypes.

Molecular & general genetics : MGG - 10 May 1994

Taura T, Akiyama Y, Ito K

Abstract excerpt

A number of secY mutants of Escherichia coli showing protein export defects were isolated by a combination of localized mutagenesis and secA-lacZ screening. Most of them were cold sensitive and contained single base substitutions in secY leading to amino acid replacements in various parts of the...

Topics

Amino Acid Sequence
Bacterial Proteins
Base Sequence
Escherichia coli
Escherichia coli Proteins
Molecular Sequence Data
Mutation
SEC Translocation Channels
Temperature
Translocation, Genetic

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