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Article

TP73 allelic expression in human brain and allele frequencies in Alzheimer's disease.

BMC medical genetics - 2 Jun 2004

Li Quanyi, Athan Eleni S, Wei Michelle, Yuan Eric, Rice Samuel L, Vonsattel Jean-Paul, Mayeux Richard P, Tycko Benjamin

Abstract excerpt

BACKGROUND: The p73 protein, a paralogue of the p53 tumor suppressor, is essential for normal development and survival of neurons. TP73 is therefore of interest as a candidate gene for Alzheimer's disease (AD) susceptibility. TP73 mRNA is transcribed from three promoters, termed P1-P3, and there is evidence for an additional complexity in its regulation, namely, a variable allelic expression bias in some human...

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Identifiers

PMID: 15175114
DOI: 10.1186/1471-2350-5-14
PMCID: PMC420466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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