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Article

Allelic expression of the putative tumor suppressor gene p73 in human fetal tissues and tumor specimens.

Biochimica et biophysica acta - 25 Apr 2000

Hu J F, Ulaner G A, Oruganti H, Ivaturi R D, Balagura K A, Pham J, Vu T H, Hoffman A R

Abstract excerpt

p73, a proposed tumor suppressor, shares significant amino acid sequence homology with p53. However, p73 is rarely mutated in tumors but it has been suggested that p73 is monoallelically expressed in some tissues. This latter feature would predispose p73 to gene inactivation because a single genetic 'hit' or the loss of the expressed parental allele would leave the cell without p73 activity. We examined the...

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PMID: 10760569
DOI: 10.1016/s0167-4781(00)00017-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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