Article
Allelic expression and quantitative RT-PCR study of TAp73 and DeltaNp73 in non-Hodgkin's lymphomas.
Leukemia research - 1 Feb 2006
Cuadros Marta, Ribas Gloria, Fernández Victoria, Rivas Carmen, Benitez Javier, Martinez-Delgado Beatriz
Abstract excerpt
p73 shares structural and functional homology to p53. p73 generates different proteins using alternative promoters and splicing which have different biological characteristics. We investigated the pattern (monoallelic or biallelic) of expression of TAp73 and DeltaNp73 in normal lymphocytes and lymphomas using two p73 polymorphisms. We found monoallelic expression of TAp73 in normal lymphocytes and tumors, and a...
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