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Article

A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPRO.

Journal of medical genetics - 1 Jun 2004

Evans D G R, Eccles D M, Rahman N, Young K, Bulman M, Amir E, Shenton A, Howell A, Lalloo F

Abstract excerpt

PURPOSE: To develop a simple scoring system for the likelihood of identifying a BRCA1 or BRCA2 mutation. METHODS: DNA samples from affected subjects from 422 non-Jewish families with a history of breast and/or ovarian cancer were screened for BRCA1 mutations and a subset of 318 was screened for BRCA2 by whole gene screening techniques. Using a combination of results from screening and the family history of...

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Source

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Identifiers

PMID: 15173236
DOI: 10.1136/jmg.2003.017996
PMCID: PMC1735807

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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