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Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of PENN II model to previous study.

Familial cancer - 1 Dec 2010

Lindor Noralane M, Johnson Kiley J, Harvey Hayden, Shane Pankratz V, Domchek Susan M, Hunt Katherine, Wilson Marcia, Cathie Smith M, Couch Fergus

Abstract excerpt

A number of models have been developed to predict the probability that a person carries a detectable germline mutation in the BRCA1 or BRCA2 genes. Their relative performance in a clinical setting is variable. To compare the performance characteristics of a web-based BRCA1/BRCA2 gene mutation pre...

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Identifiers

PMID: 20512419
DOI: 10.1007/s10689-010-9348-3
PMCID: PMC2981620

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20512419-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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