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Article

BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2, and prevalence of other breast cancer susceptibility genes.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 2002

Berry Donald A, Iversen Edwin S, Gudbjartsson Daniel F, Hiller Elaine H, Garber Judy E, Peshkin Beth N, Lerman Caryn, Watson Patrice, Lynch Henry T, Hilsenbeck Susan G, Rubinstein Wendy S, Hughes Kevin S, Parmigiani Giovanni

Abstract excerpt

PURPOSE: To compare genetic test results for deleterious mutations of BRCA1 and BRCA2 with estimated probabilities of carrying such mutations; to assess sensitivity of genetic testing; and to assess the relevance of other susceptibility genes in familial breast and ovarian cancer. PATIENTS AND METHODS: Data analyzed were from six high-risk genetic counseling clinics and concern individuals from families for which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12039933
DOI: 10.1200/JCO.2002.05.121

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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