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Article

Mutated p53 as a molecular marker for the diagnosis of head and neck cancer.

The Journal of pathology - 1 Dec 2002

van Houten Viola M M, Tabor Maarten P, van den Brekel Michiel W M, Kummer J Alain, Denkers Fedor, Dijkstra Janny, Leemans René, van der Waal Isaäc, Snow Gordon B, Brakenhoff Ruud H

Abstract excerpt

In total, 10-30% of patients with head and neck squamous cell carcinoma (HNSCC) develop local recurrences despite seemingly adequate tumour resection. This may result from minimal residual cancer (MRC): small numbers of tumour cells left behind in the surgical margins, undetectable by routine histopathology. In recent studies, p53 mutations have been considered as selective and sensitive DNA markers of cancer...

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Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Head and Neck Neoplasms

Share to Neoplasm Recurrence, Local

Share to Neoplasm, Residual

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Source

Identifiers

PMID: 12434417
DOI: 10.1002/path.1242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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