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Article

Genome-wide analysis of mRNA stability using transcription inhibitors and microarrays reveals posttranscriptional control of ribosome biogenesis factors.

Molecular and cellular biology - 1 Jun 2004

Grigull Jörg, Mnaimneh Sanie, Pootoolal Jeffrey, Robinson Mark D, Hughes Timothy R

Abstract excerpt

Using DNA microarrays, we compared global transcript stability profiles following chemical inhibition of transcription to rpb1-1 (a temperature-sensitive allele of yeast RNA polymerase II). Among the five inhibitors tested, the effects of thiolutin and 1,10-phenanthroline were most similar to rpb1-1. A comparison to various microarray data already in the literature revealed similarity between mRNA stability...

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Identifiers

PMID: 15169913
DOI: 10.1128/MCB.24.12.5534-5547.2004
PMCID: PMC419893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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