Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae.

doi:10.1093/genetics/131.4.851

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Article

Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae.

Genetics - 1 Aug 1992

Zhou Z, Elledge S J

Abstract excerpt

Ribonucleotide reductase is an essential enzyme that catalyzes the rate limiting step for production of the deoxyribonucleotides required for DNA synthesis. It is encoded by three genes, RNR1, RNR2 and RNR3, each of which is inducible by agents that damage DNA or block DNA replication. To probe t...

Topics

Alleles
Base Sequence
DNA Damage
DNA, Fungal
Gene Expression
Genes, Fungal
Genetic Complementation Test
Molecular Sequence Data
Mutation
Phenotype
Ribonucleotide Reductases
Saccharomyces cerevisiae
Transcription, Genetic

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