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Article

Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast.

G3 (Bethesda, Md.) - 5 Jul 2017

Holstein Eva-Maria, Ngo Greg, Lawless Conor, Banks Peter, Greetham Matthew, Wilkinson Darren, Lydall David

Abstract excerpt

Functional telomeres are critically important to eukaryotic genetic stability. Scores of proteins and pathways are known to affect telomere function. Here, we report a series of related genome-wide genetic interaction screens performed on budding yeast cells with acute or chronic telomere defects. Genetic interactions were examined in cells defective in Cdc13 and Stn1, affecting two components of CST, a single...

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Identifiers

PMID: 28546384
DOI: 10.1534/g3.117.042283
PMCID: PMC5499144

Genes

EXO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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