Article
The mutation of a novel Saccharomyces cerevisiae SRL4 gene rescues the lethality of rad53 and lcd1 mutations by modulating dNTP levels.
Journal of microbiology (Seoul, Korea) - 1 Feb 2008
Choi Do-Hee, Oh Young-Mi, Kwon Sung-Hun, Bae Sung-Ho
Abstract excerpt
The SRL4 (YPL033C) gene was initially identified by the screening of Saccharomyces cerevisiae genes that play a role in DNA metabolism and/or genome stability using the SOS system of Escherichia coli. In this study, we found that the srl4Delta mutant cells were resistant to the chemicals that inh...
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