Evolutionary genetics. Directed mutations slip-sliding away?

Abstract excerpt

Adaptive frameshift mutations in the lacZ gene of Escherichia coli are, unusually, nearly all short deletions, perhaps caused by slipped-strand mispairings in mononucleotide runs. But are they directed?

Topics

• Adaptation, Physiological
• Biological Evolution
• Escherichia coli
• Mutation
• Selection, Genetic
• beta-Galactosidase