Spontaneous mutations in bacteria: chance or necessity?

Abstract excerpt

Several investigators have recently reported that significant numbers of appropriately adapted mutants can be induced in bacterial and yeast strains by exposing stationary phase cells to specific environmental challenges. The resulting mutants are said to be both selection-induced and demonstrably non-random in origin; if this interpretation is correct, it is in direct conflict with the conventional neo-Darwinian...

Topics

• Adaptation, Physiological
• Bacteria
• Escherichia coli
• Models, Genetic
• Mutagenesis
• Mutation