Article
Polymorphism of Fc receptor IIa for IgG in infants is associated with susceptibility to perinatal HIV-1 infection.
AIDS (London, England) - 21 May 2004
Brouwer Kimberly C, Lal Renu B, Mirel Lisa B, Yang Chunfu, van Eijk Anne M, Ayisi John, Otieno Juliana, Nahlen Bernard L, Steketee Richard, Lal Altaf A, Shi Ya Ping
Abstract excerpt
OBJECTIVE: To evaluate the effect of polymorphism of the Fc gamma receptor IIa, which is associated with differential human IgG subclass binding, on perinatal HIV-1 transmission. METHODS: Fc gamma RIIa genotype was tested in 448 HIV-seropositive mothers and their infants from a cohort study designed to assess the effect of placental malaria on HIV vertical transmission conducted from 1996 to 2001 in western...
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