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Article

Perinatal HIV-1 transmission: Fc gamma receptor variability associates with maternal infectiousness and infant susceptibility.

Retrovirology - 10 Jun 2016

Lassaunière Ria, Musekiwa Alfred, Gray Glenda E, Kuhn Louise, Tiemessen Caroline T

Abstract excerpt

BACKGROUND: Accumulating data suggest that immune effector functions mediated through the Fc portion of HIV-1-specific immunoglobulin G (IgG) are a key component of HIV-1 protective immunity, affecting both disease progression and HIV-1 acquisition. Through studying Fc gamma receptor (FcγR) variants known to alter IgG Fc-mediated immune responses, we indirectly assessed the role of FcγR-mediated effector...

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Share to Antibody-Dependent Cell Cytotoxicity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Antibodies

Share to Immunoglobulin G

Share to Infectious Disease Transmission, Vertical

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Share to Pregnancy Complications, Infectious

Share to Receptors, IgG

Source

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Identifiers

PMID: 27287460
DOI: 10.1186/s12977-016-0272-y
PMCID: PMC4902924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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