Article
Polymorphism of Fc receptor IIa for immunoglobulin G is associated with placental malaria in HIV-1-positive women in western Kenya.
The Journal of infectious diseases - 15 Sept 2004
Brouwer Kimberly C, Lal Altaf A, Mirel Lisa B, Otieno Juliana, Ayisi John, Van Eijk Anne M, Lal Renu B, Steketee Richard, Nahlen Bernard L, Shi Ya Ping
Abstract excerpt
BACKGROUND: Genetic polymorphism of the Fc receptor IIa for immunoglobulin (Ig) G (Fc gamma RIIa) determines IgG subclass binding. Previous studies have shown that individuals with the IgG1/3-binding Fc gamma RIIa-Arg/Arg131 genotype are relatively protected against high-density malaria, whereas...
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