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Article

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.

BMC infectious diseases - 20 Apr 2017

Munde Elly O, Okeyo Winnie A, Raballah Evans, Anyona Samuel B, Were Tom, Ong'echa John M, Perkins Douglas J, Ouma Collins

Abstract excerpt

BACKGROUND: Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of opsonized microbes, thereby, linking humoral and cellular immunity. FcγR polymorphisms influence binding affinity to IgGs and consequently, can influence clinical malaria outcomes. Specifically,...

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Identifiers

PMID: 28427365
DOI: 10.1186/s12879-017-2390-0
PMCID: PMC5397742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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