Article

IgG is differentially and selectively transferred across the placenta in HIV-infected women

2018-11-30

Abstract excerpt

SUMMARY The transplacental transfer of maternal IgG to the developing fetus is critical for infant protection against infectious pathogens in the first year of life. However, factors that modulate the transplacental transfer efficiency of maternal IgG that could be harnessed for maternal vaccine design remain largely undefined. HIV-infected women have impaired placental IgG transfer, yet the mechanism underlying t...

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Literature Corpus work: eea20247-33ea-5b7d-9350-f827a7edc870
DOI: 10.1101/479121

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