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Article

Association of SNPs in HLA-C and ZNRD1 Genes With HIV-1 Mother-to-Child Transmission in Zambia Population.

Journal of acquired immune deficiency syndromes (1999) - 1 Apr 2021

Celerino da Silva Ronaldo, Segat Ludovica, Kuhn Louise, Chies José Artur Bogo, Crovella Sergio

Abstract excerpt

BACKGROUND: Human leukocyte antigen C (HLA-C) and Zinc ribbon domain containing 1 (ZNRD1) are considered HIV-1 restriction factors and are expressed in the placenta. Variations in HLA-C and ZNRD1 genes are known to influence HIV-1 infection, including viral replication and progression to AIDS. Little is known about the role of variants in these genes in HIV-1 mother-to-child transmission. METHODS: We evaluated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33252547
DOI: 10.1097/QAI.0000000000002584

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