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Article

Arrested pulmonary alveolar cytodifferentiation and defective surfactant synthesis in mice missing the gene for parathyroid hormone-related protein.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2004

Rubin Lewis P, Kovacs Christopher S, De Paepe Monique E, Tsai Shu-Whei, Torday John S, Kronenberg Henry M

Abstract excerpt

Parathyroid hormone-related protein (PTHrP) and PTH/PTHrP receptor expression are developmentally regulated in lung epithelium and adepithelial mesenchyme, respectively. To test the hypothesis that PTHrP is a developmental regulator of terminal airway development, we investigated in vivo and in vitro models of alveolar cytodifferentiation using mice in which the gene encoding PTHrP was ablated by homologous...

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PMID: 15162506
DOI: 10.1002/dvdy.20058

Genes

PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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