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Article

Unsuspected effects of a lung-specific Cre deleter mouse line.

Genesis (New York, N.Y. : 2000) - 1 Mar 2011

Jeannotte Lucie, Aubin Josée, Bourque Sylvie, Lemieux Margot, Montaron Séverine, Provencher St-Pierre Anne

Abstract excerpt

Cre-expressing mouse lines constitute an important asset to mammalian genetics, allowing the deletion of genes in a spatio-temporal specific manner. Our study on Hox gene function in lung development has led us to use a lung endoderm-specific deletion with the Sftpc-cre mouse line expressing the Cre recombinase gene under the control of human surfactant protein C regulatory sequences. In control experiments, the...

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PMID: 21309069
DOI: 10.1002/dvg.20720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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