Article
Mesenchymal maintenance of distal epithelial cell phenotype during late fetal lung development.
American journal of physiology. Lung cellular and molecular physiology - 1 Mar 2007
Deimling Julie, Thompson Kate, Tseu Irene, Wang Jinxia, Keijzer Richard, Tanswell A Keith, Post Martin
Abstract excerpt
Classical tissue recombination experiments have reported that at early gestation both tracheal and distal lung epithelium have the plasticity to respond to mesenchymal signals. Herein we examined the role of epithelial-mesenchymal interactions in maintaining epithelial differentiation at late (E19-E21, term = 22 days) fetal gestation in the rat. Isolated distal lung epithelial cells were recombined with...
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