Article
Parathyroid hormone-related protein is required for tooth eruption.
Proceedings of the National Academy of Sciences of the United States of America - 29 Sept 1998
Philbrick W M, Dreyer B E, Nakchbandi I A, Karaplis A C
Abstract excerpt
Parathyroid hormone (PTH)-related protein (PTHrP)-knockout mice die at birth with a chondrodystrophic phenotype characterized by premature chondrocyte differentiation and accelerated bone formation, whereas overexpression of PTHrP in the chondrocytes of transgenic mice produces a delay in chondro...
Topics
- Animals
- Chondrocytes
- Dental Enamel
- Epithelium
- Female
- Gene Expression
- In Situ Hybridization
- Male
- Mice
- Mice, Knockout
- Mice, Transgenic
- Parathyroid Hormone-Related Protein
- Phenotype
- Proteins
- RNA, Messenger
- Receptor, Parathyroid Hormone, Type 1
- Receptors, Parathyroid Hormone
- Tooth Eruption