Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population-based case-control study of CYP11A gene polymorphism and breast cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2004

Zheng Wei, Gao Yu-Tang, Shu Xiao-Ou, Wen Wanqing, Cai Qiuyin, Dai Qi, Smith Jeffrey R

Abstract excerpt

The CYP11A gene encodes the cholesterol side-chain cleavage enzyme (P450scc) that catalyzes the first and rate-limiting step for the biosynthesis of sex hormones. A pentanucleotide repeat [(TAAAA)n] polymorphism in the 5' of the CYP11A gene has been reported to be related to the risk of polycystic ovary syndrome, an inherited endocrine disorder characterized by hyperandrogenemia. We investigated the association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Distribution
Share to Cholesterol Side-Chain Cleavage Enzyme

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Confidence Intervals

Share to Incidence

Share to Population Surveillance

Share to Probability

Share to Reference Values

Share to Risk Assessment

Source

Identifiers

PMID: 15159300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population-based case-control study of CYP11A gene polymorphism and breast cancer risk.PMID 15159300Read ↗

Risk-association of CYP11A1 polymorphisms and breast cancer among Han Chinese women in Southern China.Semantic proximity Read ↗

Polymorphisms in CYP1A1 and breast carcinoma risk in a population-based case-control study of Chinese women.Semantic proximity Read ↗

CYP11A1 microsatellite (tttta)n polymorphism in PCOS women from South India.Semantic proximity Read ↗

Haplotype analysis of CYP11A1 identifies promoter variants associated with breast cancer risk.Semantic proximity Read ↗

Polymorphisms in steroid hormone biosynthesis genes and risk of breast cancer and fibrocystic breast conditions in Chinese women.Semantic proximity Read ↗

Association between polymorphisms of the CYP11A1 gene and polycystic ovary syndrome in Chinese women.Semantic proximity Read ↗

Polymorphisms in the CYP19A1 (aromatase) gene and endometrial cancer risk in Chinese women.Semantic proximity Read ↗

A systematic assessment of common genetic variation in CYP11A and risk of breast cancer.Semantic proximity Read ↗

Variants in hormone biosynthesis genes and risk of endometrial cancer.Semantic proximity Read ↗

Association between CYP17 polymorphisms and the development of breast cancer.Semantic proximity Read ↗

Frequencies of promoter pentanucleotide (TTTTA)n of CYP11A gene in European and North African populations.Semantic proximity Read ↗

Analysis of 17beta-hydroxysteroid dehydrogenase types 5, 7, and 12 genetic sequence variants in breast cancer cases from French Canadian Families with high risk of breast and ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.