Article
Variants in hormone biosynthesis genes and risk of endometrial cancer.
Cancer causes & control : CCC - 1 Nov 2008
Olson Sara H, Orlow Irene, Bayuga Sharon, Sima Camelia, Bandera Elisa V, Pulick Katherine, Faulkner Shameka, Tommasi Diana, Egan Daniel, Roy Pampa, Wilcox Homer, Asya Ali, Modica Ippolito, Asad Haider, Soslow Robert, Zauber Ann G
Abstract excerpt
We investigated the risk associated with variants in three genes involved in estrogen biosynthesis, CYP11A1, CYP17A1, and CYP19A1, in the population-based case-control study of Estrogen, Diet, Genetics, and Endometrial Cancer. This study was conducted in New Jersey in 2001-2006 with 417 cases and 402 controls. For CYP11A1, there was no association between the number of [TTTTA]( n ) repeats (D15S520) and risk. For...
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