Article
Association between polymorphisms of the CYP11A1 gene and polycystic ovary syndrome in Chinese women.
Molecular biology reports - 1 Aug 2012
Zhang Cheng-Wei, Zhang Xin-Lin, Xia Yan-Jie, Cao Yun-Xia, Wang Wen-Jun, Xu Pei, Che Ye-Na, Wu Xiao-Ke, Yi Long, Gao Qian, Wang Yong
Abstract excerpt
The cholesterol side chain cleavage enzyme (CYP11A1) gene plays an important part in the synthesis of sex hormones and has been reported to be involved in the pathogenesis of polycystic ovary syndrome. A case-control study including 314 PCOS patients and 314 controls was conducted to assess the association of the SNPs rs4077582 and rs11632698 in CYP11A1 with PCOS using the polymerase chain reaction-restriction...
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