Article
Generation of a DNA microarray for determination of E6 natural variants of human papillomavirus type 16.
Journal of virological methods - 1 Aug 2004
Gemignani Federica, Landi Stefano, Chabrier Amélie, Smet Anouk, Zehbe Ingeborg, Canzian Federico, Tommasino Massimo
Abstract excerpt
Infection with high-risk types of human papillomavirus (HPV) is necessary for the development of cervical cancer. However, the majority of the HPV infections are efficiently cleared by the immune system and only a minority persist and induce the development of malignant lesions. Several studies provided evidence that intratype genetic variations are implicated in determining the clinical outcome of HPV...
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