Article
Development and evaluation of a highly sensitive human papillomavirus genotyping DNA chip.
Gynecologic oncology - 1 Jan 2006
Kim Ki Hyung, Yoon Man Soo, Na Yong Jin, Park Chang Soo, Oh Myung Ryurl, Moon Woo Chul
Abstract excerpt
OBJECTIVES: Test of human papillomavirus (HPV) is a useful adjunctive tool of Pap smear to screen cervical cancer. We have developed a novel HPV genotyping DNA chip arrayed by multiple oligonucleotide probes of both L1 and E6/E7 gene sequence of 42 types of anogenital HPV. METHODS: Consensus PCR...
Topics
- Adult
- Aged
- Base Sequence
- Conserved Sequence
- DNA, Neoplasm
- DNA, Viral
- Female
- Genotype
- Humans
- Middle Aged
- Molecular Sequence Data
- Oligonucleotide Array Sequence Analysis
- Papillomaviridae
- Papillomavirus Infections
- Sensitivity and Specificity
- Uterine Cervical Neoplasms
- Uterine Cervical Dysplasia