Article
Development and evaluation of a highly sensitive human papillomavirus genotyping DNA chip.
Gynecologic oncology - 1 Jan 2006
Kim Ki Hyung, Yoon Man Soo, Na Yong Jin, Park Chang Soo, Oh Myung Ryurl, Moon Woo Chul
Abstract excerpt
OBJECTIVES: Test of human papillomavirus (HPV) is a useful adjunctive tool of Pap smear to screen cervical cancer. We have developed a novel HPV genotyping DNA chip arrayed by multiple oligonucleotide probes of both L1 and E6/E7 gene sequence of 42 types of anogenital HPV. METHODS: Consensus PCR products of L1 and E6/E7 gene sequences of HPV are hybridized to arrayed probes on the HPV chip and HPV genotypes are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
