Article
Contribution of the SgIGSF adhesion molecule to survival of cultured mast cells in vivo.
Biochemical and biophysical research communications - 18 Jun 2004
Ito Akihiko, Koma Yu-ichiro, Watabe Kenji, Jippo Tomoko, Wakayama Tomohiko, Iseki Shoichi, Kitamura Yukihiko
Abstract excerpt
Spermatogenic immunoglobulin superfamily (SgIGSF) is a recently identified adhesion molecule, and the microphthalmia transcription factor (MITF) was essential for its expression in mast cells. Since the tg mutant allele is practically a null mutation of the MITF gene, cultured mast cells (CMCs) derived from (WBxC57BL/6)F(1) (F(1))-tg/tg mice did not express SgIGSF whereas CMCs from F(1)-wild-type (+/+) mice...
Topics
- Alleles
- Animals
- Blotting, Western
- Cell Adhesion
- Cell Adhesion Molecule-1
- Cell Adhesion Molecules
- Cell Survival
- Coculture Techniques
- DNA, Complementary
- DNA-Binding Proteins
- Fibroblasts
- Genetic Vectors
- Immunoglobulins