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Article

Impaired expression of integrin alpha-4 subunit in cultured mast cells derived from mutant mice of mi/mi genotype.

Blood - 15 Sept 1998

Kim D K, Morii E, Ogihara H, Hashimoto K, Oritani K, Lee Y M, Jippo T, Adachi S, Kanakura Y, Kitamura Y

Abstract excerpt

The mi locus encodes a member of the basic-helix-loop-helix-leucine zipper protein family of transcription factors (hereafter called MITF). We have reported that expression of several genes was impaired in cultured mast cells (CMCs) of mi/mi mice due to a defective transactivation ability of mutant MITF (mi-MITF). Because attachment of mi/mi CMCs to fibroblasts is impaired, we examined the expression of integrin...

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Source

Identifiers

PMID: 9731055

Genes

MITF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Impaired expression of integrin alpha-4 subunit in cultured mast cells derived from mutant mice of mi/mi genotype.PMID 9731055Read ↗

Deficient transcription of mouse mast cell protease 4 gene in mutant mice of mi/mi genotype.Semantic proximity Read ↗

Inhibitory effect of the transcription factor encoded by the mi mutant allele in cultured mast cells of mice.Semantic proximity Read ↗

Different effect of various mutant MITF encoded by mi, Mior, or Miwh allele on phenotype of murine mast cells.Semantic proximity Read ↗

Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of miceSemantic proximity Read ↗

Dual abnormal effects of mutant MITF encoded by Mi(wh) allele on mouse mast cells: decreased but recognizable transactivation and inhibition of transactivation.Semantic proximity Read ↗

Low c-kit expression of cultured mast cells of mi/mi genotype may be involved in their defective responses to fibroblasts that express the ligand for c-kit.Semantic proximity Read ↗

Inhibitory effect of the transcription factor encoded by the mutant mi microphthalmia allele on transactivation of mouse mast cell protease 7 gene.Semantic proximity Read ↗

Cell type-specific deficiency of c-kit gene expression in mutant mice of mi/mi genotype.Semantic proximity Read ↗

SgIGSF: a new mast-cell adhesion molecule used for attachment to fibroblasts and transcriptionally regulated by MITF.Semantic proximity Read ↗

Additive effect of mouse genetic background and mutation of MITF gene on decrease of skin mast cells.Semantic proximity Read ↗

Effect of MITF on mast cell differentiation.Semantic proximity Read ↗

Inhibitory effect of the mi transcription factor encoded by the mutant mi allele on GA binding protein-mediated transcript expression in mouse mast cells.Semantic proximity Read ↗

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