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Article

SgIGSF: a new mast-cell adhesion molecule used for attachment to fibroblasts and transcriptionally regulated by MITF.

Blood - 1 Apr 2003

Ito Akihiko, Jippo Tomoko, Wakayama Tomohiko, Morii Eiichi, Koma Yu-ichiro, Onda Hiroaki, Nojima Hiroshi, Iseki Shoichi, Kitamura Yukihiko

Abstract excerpt

Microphthalmia transcription factor (MITF) is a basic-helix-loop-helix-leucine zipper-type transcription factor. The mutant mi and Mi(wh) alleles encode MITFs with deletion and alteration of a single amino acid, respectively, whereas the tg is a null mutation. In coculture with NIH/3T3 fibroblasts, the numbers of cultured mast cells (CMCs) derived from C57BL/6 (B6)(mi/mi), B6(Miwh/Miwh), and B6(tg/tg) mice that...

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Source

Identifiers

PMID: 12456501
DOI: 10.1182/blood-2002-07-2265

Genes

MITF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SgIGSF: a new mast-cell adhesion molecule used for attachment to fibroblasts and transcriptionally regulated by MITF.PMID 12456501Read ↗

Contribution of the SgIGSF adhesion molecule to survival of cultured mast cells in vivo.Semantic proximity Read ↗

Distinct role for c-kit receptor tyrosine kinase and SgIGSF adhesion molecule in attachment of mast cells to fibroblasts.Semantic proximity Read ↗

Impaired expression of integrin alpha-4 subunit in cultured mast cells derived from mutant mice of mi/mi genotype.Semantic proximity Read ↗

Distinct roles for the SgIGSF adhesion molecule and c-kit receptor tyrosine kinase in the interaction between mast cells and the mesentery.Semantic proximity Read ↗

Dual abnormal effects of mutant MITF encoded by Mi(wh) allele on mouse mast cells: decreased but recognizable transactivation and inhibition of transactivation.Semantic proximity Read ↗

Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of miceSemantic proximity Read ↗

Inhibitory effect of the transcription factor encoded by the mi mutant allele in cultured mast cells of mice.Semantic proximity Read ↗

Inhibitory effect of the mi transcription factor encoded by the mutant mi allele on GA binding protein-mediated transcript expression in mouse mast cells.Semantic proximity Read ↗

Regulation of mast cell phenotype by MITF.Semantic proximity Read ↗

Number of mast cells in the peritoneal cavity of mice: influence of microphthalmia transcription factor through transcription of newly found mast cell adhesion molecule, spermatogenic immunoglobulin superfamily.Semantic proximity Read ↗

Inhibitory effect of the transcription factor encoded by the mutant mi microphthalmia allele on transactivation of mouse mast cell protease 7 gene.Semantic proximity Read ↗

Deficient transcription of mouse mast cell protease 4 gene in mutant mice of mi/mi genotype.Semantic proximity Read ↗

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