Expression pattern, subcellular localization and structure–function relationship of rat Tpx‐1, a spermatogenic cell adhesion molecule responsible for association with Sertoli cells

Abstract excerpt

The gene for a testicular cell adhesion protein called Tpx-1, which mediates the binding of spermatogenic cells to Sertoli cells of the rat in primary culture, was previously cloned. Here the characterization of Tpx-1 is reported. Tpx-1 messenger ribonucleic acid (mRNA) became detectable in pachytene spermatocytes and continued to be present throughout development into elongated spermatids, while the amount of...

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