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Article

Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes.

BMC genetics - 24 May 2004

Long Ji-Rong, Zhao Lan-Juan, Liu Peng-Yuan, Lu Yan, Dvornyk Volodymyr, Shen Hui, Liu Yong-Jun, Zhang Yuan-Yuan, Xiong Dong-Hai, Xiao Peng, Deng Hong-Wen

Abstract excerpt

BACKGROUND: The adequacy of association studies for complex diseases depends critically on the existence of linkage disequilibrium (LD) between functional alleles and surrounding SNP markers. RESULTS: We examined the patterns of LD and haplotype distribution in eight candidate genes for osteoporosis and/or obesity using 31 SNPs in 1,873 subjects. These eight genes are apolipoprotein E (APOE), type I collagen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15157284
DOI: 10.1186/1471-2156-5-11
PMCID: PMC421754

Genes

PTH
UCP3
APOE
LEPR
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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