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Article

Single nucleotide polymorphisms in bone turnover-related genes in Koreans: ethnic differences in linkage disequilibrium and haplotype.

BMC medical genetics - 26 Nov 2007

Kim Kyung-Seon, Kim Ghi-Su, Hwang Joo-Yeon, Lee Hye-Ja, Park Mi-Hyun, Kim Kwang-joong, Jung Jongsun, Cha Hyo-Soung, Shin Hyoung Doo, Kang Jong-Ho, Park Eui Kyun, Kim Tae-Ho, Hong Jung-Min, Koh Jung-Min, Oh Bermseok, Kimm Kuchan, Kim Shin-Yoon, Lee Jong-Young

Abstract excerpt

BACKGROUND: Osteoporosis is defined as the loss of bone mineral density that leads to bone fragility with aging. Population-based case-control studies have identified polymorphisms in many candidate genes that have been associated with bone mass maintenance or osteoporotic fracture. To investigate single nucleotide polymorphisms (SNPs) that are associated with osteoporosis, we examined the genetic variation among...

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PMID: 18036257
DOI: 10.1186/1471-2350-8-70
PMCID: PMC2222243

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