Article
Promoter and 3'-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study.
American journal of human genetics - 1 Nov 2005
Fang Yue, van Meurs Joyce B J, d'Alesio Arnold, Jhamai Mila, Zhao Hongyan, Rivadeneira Fernando, Hofman Albert, van Leeuwen Johannes P T, Jehan Frédéric, Pols Huibert A P, Uitterlinden André G
Abstract excerpt
Polymorphisms of the vitamin D receptor gene (VDR) have been shown to be associated with several complex diseases, including osteoporosis, but the mechanisms are unknown and study results have been inconsistent. We therefore determined sequence variation across the major relevant parts of VDR, in...
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