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Article

Heterogeneity of linkage disequilibrium in human genes has implications for association studies of common diseases.

Human molecular genetics - 15 Feb 2002

Tiret Laurence, Poirier Odette, Nicaud Viviane, Barbaux Sandrine, Herrmann Stefan-Martin, Perret Claire, Raoux Ségolène, Francomme Carole, Lebard Géraud, Trégouët David, Cambien François

Abstract excerpt

Linkage disequilibrium (LD) is the central concept of genetic association studies. Although LD has been shown not to be uniformly distributed across the genome, limited information is available about the characteristics of LD within candidate genes at large. We screened coding and regulatory regions of 50 candidate genes for cardiovascular diseases and identified 228 polymorphisms. The overall sequence diversity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11854174
DOI: 10.1093/hmg/11.4.419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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