Article
Assessing the patterns of linkage disequilibrium in genic regions of the human genome.
The FEBS journal - 1 Oct 2011
Sun Peng, Zhang Ruijie, Jiang Yongshuai, Wang Xing, Li Jin, Lv Hongchao, Tang Guoping, Guo Xiaodan, Meng Xianwen, Zhang Haikun, Zhang Ruimin
Abstract excerpt
We used the genotyping data generated by the International HapMap Project to study the patterns of linkage disequilibrium (LD) in human genic regions. LD patterns for 11,998 genes from 11 HapMap populations were identified by analyzing the distribution of haplotype blocks. The genes were prioritized using LD levels. The results showed that there were significant differences in the degree of LD between genes....
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