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Article

Signal transducer and activator of transcription 3 activation by the delta-opioid receptor via Galpha14 involves multiple intermediates.

Molecular pharmacology - 1 Jun 2004

Lo Rico K H, Wong Yung H

Abstract excerpt

The hematopoietic-specific Galpha14 links a variety of G protein-coupled receptors to phospholipase Cbeta (PLCbeta) stimulation. Recent studies reveal that several Galpha subunits are capable of activating signal transducer and activator of transcription (STAT) proteins. In the present study, we investigated the mechanism by which Galpha14 mediates receptor-induced stimulation of STAT3. In human embryonic kidney...

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Topics

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Share to CSK Tyrosine-Protein Kinase
Share to GTP-Binding Protein alpha Subunits, Gq-G11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterotrimeric GTP-Binding Proteins

Share to Phospholipase C beta

Share to rac1 GTP-Binding Protein

Share to Receptors, Opioid, delta

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Source

Identifiers

PMID: 15155836
DOI: 10.1124/mol.65.6.1427

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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