Article
Galpha12 and Galpha13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells.
The Journal of biological chemistry - 30 Aug 1996
Voyno-Yasenetskaya T A, Faure M P, Ahn N G, Bourne H R
Abstract excerpt
Many growth factors and agonists for G protein-coupled receptors activate mitogen-activated protein (MAP) kinase pathways, including the extracellular signal-regulated kinase (ERK) pathway and the c-Jun kinase (JNK) pathway. Transient transfection of dominant negative and constitutively active pa...
Topics
- Animals
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Line
- Enzyme Activation
- GTP-Binding Proteins
- JNK Mitogen-Activated Protein Kinases
- Mitogen-Activated Protein Kinases
- Mutation
- Protein Kinase Inhibitors
- Protein Kinases
- Recombinant Fusion Proteins
- Signal Transduction