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Article

Activation of STAT3 by specific Galpha subunits and multiple Gbetagamma dimers.

The international journal of biochemistry & cell biology - 1 Jun 2010

Yuen Jessie W F, Poon Lydia S W, Chan Anthony S L, Yu Frances W Y, Lo Rico K H, Wong Yung H

Abstract excerpt

The hematopoietic-specific G(q) subfamily members, Galpha(16) and Galpha(14) proteins have recently been shown to be capable of stimulating the signal transducer and activator of transcription 3 (STAT3) as well as STAT1. In the present study we examined whether this activation was STAT-member specific as well as determining the possible involvement of Gbetagamma dimers. Despite clear stimulation of STAT3, the...

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Source

Identifiers

PMID: 20348012
DOI: 10.1016/j.biocel.2010.03.017

Genes

STAT3
STAT1
STAT2
STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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