Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of nick-directed DNA mismatch repair and loop repair in human cells.

The Journal of biological chemistry - 16 Jul 2004

Huang Yao-Ming, Chen Shee-Uan, Goodman Steven D, Wu Shang-Hsin, Kao Jau-Tsuen, Lee Chun-Nan, Cheng Wern-Cherng, Tsai Keh-Sung, Fang Woei-horng

Abstract excerpt

In human cells, large DNA loop heterologies are repaired through a nick-directed pathway independent of mismatch repair. However, a 3'-nick generated by bacteriophage fd gene II protein heterology is not capable of stimulating loop repair. To evaluate the possibility that a mismatch near a loop could induce both repair types in human cell extracts, we constructed and tested a set of DNA heteroduplexes, each of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Pair Mismatch
Share to Base Pairing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Damage

Share to Endonucleases

Share to HeLa Cells

Share to Nucleic Acid Conformation

Share to Nucleic Acid Heteroduplexes

Share to Substrate Specificity

Source

Identifiers

PMID: 15151992
DOI: 10.1074/jbc.M401675200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of nick-directed DNA mismatch repair and loop repair in human cells.PMID 15151992Read ↗

Nick-directed repair of palindromic loop mismatches in human cell extracts.Semantic proximity Read ↗

Bi-directional Processing of DNA Loops by Mismatch Repair-dependent and -independent Pathways in Human CellsSemantic proximity Read ↗

Efficient repair of large DNA loops in Saccharomyces cerevisiae.Semantic proximity Read ↗

A possible mechanism for exonuclease 1-independent eukaryotic mismatch repairSemantic proximity Read ↗

Mismatch repair of heteroduplex DNA intermediates of extrachromosomal recombination in mammalian cells.Semantic proximity Read ↗

Repair of Large Insertion/Deletion Heterologies in Human Nuclear Extracts Is Directed by a 5′ Single-strand Break and Is Independent of the Mismatch Repair SystemSemantic proximity Read ↗

Mismatch repair inhibits homeologous recombination via coordinated directional unwinding of trapped DNA structures.Semantic proximity Read ↗

Initiation of DNA interstrand cross-link repair in humans: the nucleotide excision repair system makes dual incisions 5' to the cross-linked base and removes a 22- to 28-nucleotide-long damage-free strand.Semantic proximity Read ↗

Recognition and Repair of Compound DNA Lesions (Base Damage and Mismatch) by Human Mismatch Repair and Excision Repair SystemsSemantic proximity Read ↗

Double displacement loops (double d-loops) are templates for oligonucleotide-directed mutagenesis and gene repair.Semantic proximity Read ↗

Stabilization of diverged tandem repeats by mismatch repair: evidence for deletion formation via a misaligned replication intermediate.Semantic proximity Read ↗

Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.