Mismatch repair of heteroduplex DNA intermediates of extrachromosomal recombination in mammalian cells.

doi:10.1128/mcb.14.1.400-406.1994

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Article

Mismatch repair of heteroduplex DNA intermediates of extrachromosomal recombination in mammalian cells.

Molecular and cellular biology - 1 Jan 1994

Deng W P, Nickoloff J A

Abstract excerpt

Previous work indicated that extrachromosomal recombination in mammalian cells could be explained by the single-strand annealing (SSA) model. This model predicts that extrachromosomal recombination leads to nonconservative crossover products and that heteroduplex DNA (hDNA) is formed by annealing...

Topics

Alleles
Animals
CHO Cells
Chromosome Mapping
Cricetinae
Crossing Over, Genetic
DNA
DNA Repair
Models, Genetic
Mutation
Neomycin
Nucleic Acid Heteroduplexes
Phenotype
Recombination, Genetic

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