Article
Glucocorticoid activation of the neuronal nicotinic acetylcholine receptor alpha7 subunit gene: involvement of transcription factor Egr-1.
FEBS letters - 21 May 2004
Carrasco-Serrano Carmen, Criado Manuel
Abstract excerpt
The alpha7 subunit is a component of nicotinic acetylcholine receptors expressed in bovine chromaffin cells. The peculiar localization of these receptors at adrenomedullary areas adjacent to the adrenal cortex suggests that factors, probably glucocorticoids, arising from the cortex might diffuse and regulate alpha7 receptor expression. In reporter gene transfection experiments, dexamethasone increased alpha7...
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