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Article

Transcriptional analysis of acetylcholine receptor alpha 3 gene promoter motifs that bind Sp1 and AP2.

The Journal of biological chemistry - 14 Apr 1995

Yang X, Fyodorov D, Deneris E S

Abstract excerpt

In this study, we performed an analysis of the neuronal nicotinic acetylcholine receptor alpha 3 subunit gene promoter region, -238/+47, to identify cis and trans elements that are important for basal activity in PC12 cells. Sequence analyses of the alpha 3 promoter and footprint assays revealed an Sp1 binding site between -79 and -57 (termed the alpha 3 GA motif) and an AP2 binding site between -30 and -7. Using...

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PMID: 7721749
DOI: 10.1074/jbc.270.15.8514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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