Article
Transcriptional analysis of acetylcholine receptor alpha 3 gene promoter motifs that bind Sp1 and AP2.
The Journal of biological chemistry - 14 Apr 1995
Yang X, Fyodorov D, Deneris E S
Abstract excerpt
In this study, we performed an analysis of the neuronal nicotinic acetylcholine receptor alpha 3 subunit gene promoter region, -238/+47, to identify cis and trans elements that are important for basal activity in PC12 cells. Sequence analyses of the alpha 3 promoter and footprint assays revealed...
Topics
- Animals
- Base Sequence
- Cell Line
- DNA-Binding Proteins
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- PC12 Cells
- Promoter Regions, Genetic
- Protein Binding
- Rats
- Receptors, Cholinergic
