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Article

Regulation of rat dopamine beta-hydroxylase gene transcription by early growth response gene 1 (Egr1).

Brain research - 8 Feb 2008

Cheng Shu-Yuan, Serova Lidia I, Glazkova Dina, Sabban Esther L

Abstract excerpt

Egr1, a transcription factor rapidly induced by various stimuli including stress, can elevate transcription of genes for the catecholamine biosynthetic enzymes TH and PNMT. To examine if Egr1 also regulates dopamine beta-hydroxylase (DBH) gene expression, PC12 cells were transfected with expression vector for full length or truncated inactive Egr1 and various DBH promoter-driven luciferase constructs. While Egr1...

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Source

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Identifiers

PMID: 18190898
DOI: 10.1016/j.brainres.2007.11.055
PMCID: PMC2366081

Genes

DBH
PNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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