Article
Polymorphism of the platelet glycoprotein IIIa gene in patients with coronary stenosis.
Thrombosis and haemostasis - 1 Jun 1998
Garcia-Ribes M, Gonzalez-Lamuño D, Hernandez-Estefania R, Colman T, Pocovi M, Delgado-Rodriguez M, Garcia-Fuentes M, Revuelta J M
Abstract excerpt
Based on genetic variability, structural differences in the glycoprotein IIb/IIIa platelet receptor for adhesive proteins result in individual differences in the thrombogenicity of platelets. Recent studies suggest a controversial association between a genetic polymorphism of the glycoprotein IIIa gene (PlA2) and the risk of coronary artery disease. In our study, the prevalence of the PlA2 allele in a group of...
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